June 4, 2026

Fresh Take: Gillian Goddard on How Hormones Affect Our Health At All Ages

What do we misunderstand about how hormones affect our health, especially when it comes to women's bodies? Endocrinologist Gillian Goddard, author of the new book THE HORMONE LOOP, explains how hormones influence critical bodily functions.

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What do hormones actually do—and why are they often misunderstood? We talk with Dr. Gillian Goddard, an endocrinologist and author of The Hormone Loop: An Empowering Guide to Restoring Hormonal Harmony from Puberty to Menopause. Dr. Goddard explains how hormones affect far more than reproduction, influencing everything from metabolism and sleep to mood, stress responses, and cardiovascular health.

She breaks down the concept of the "hormone loop" and explains the four major hormonal systems that work together to keep our bodies functioning: reproductive, thyroid, growth hormone, and adrenal (stress) loops. The conversation explores how hormonal changes during puberty, pregnancy, perimenopause, and menopause can affect the entire body—not just reproductive health.

We also discuss why women's symptoms are so often dismissed, how cultural attitudes about hormones can prevent women from seeking care, and why tracking symptoms can help patients advocate for themselves more effectively.

Other topics include:

  • The relationship between estrogen, the immune system, and thyroid disorders
  • Hormone replacement therapy: benefits, misconceptions, and current research
  • The role of GLP-1 medications in midlife health and weight management

Here's where you can find Dr. Goddard:

What Fresh Hell is co-hosted by Amy Wilson and Margaret Ables.

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